Isolated primary immunoglobulin M deficiency
SELECTIVE IMMUNOGLOBULIN DEFICIENCY DISEASE THATIS A DYSGAMMAGLOBULINEMIA RESULTING FROM DECREASED LEVELS OF IMMUNOGLOBULIN M (IGM) PRODUCTION TO RODUCTION OF OTHER ANTIBODIES
Selective deficiency of immunoglobulin M; IgM deficiency; Isolated primary IgM deficiency; Immunoglobulin M deficiency; Selective IgM immunodeficiency
Isolated primary immunoglobulin M deficiency is a poorly defined dysgammaglobulinemia characterized by decreased levels of IgM while levels of other immunoglobulins are normal. The immunodeficiency has been associated with some clinical disorders including recurrent infections, atopy, Bloom's syndrome, celiac disease, systemic lupus erythematosus and malignancy, but, surprisingly, SIgMD seems to also occur in asymptomatic individuals.